what diabetes medications cause weight loss

Among diabetes medications, certain ones can lead to weight loss. They operate through various mechanisms, such as enhancing the excretion of sugar in urine, curbing appetite, or boosting insulin sensitivity in the body.

Firstly, a category of drugs called sodium-glucose cotransporter 2 (SGLT2) inhibitors prevent the kidneys from reabsorbing glucose, which allows the excess sugar to be excreted through urine. This mechanism not only aids in managing blood glucose levels but may also result in weight reduction, as the body loses some water along with the sugar. Secondly, drugs known as glucagon-like peptide-1 receptor agonists (GLP-1RA) slow down gastric emptying, which reduces food intake and consequently helps in weight loss. These medications also enhance insulin secretion from the pancreas and curb the release of glucagon, which further improves glycemic control. Additionally, biguanide drugs like metformin can facilitate weight loss by reducing hepatic glucose production, increasing glucose uptake by muscle cells, and potentially suppressing appetite.

Ultimately, for individuals with diabetes, the selection of appropriate medication should be made under a physician's guidance and not independently decided. Moreover, alongside pharmacological treatment, maintaining a balanced diet and engaging in regular physical activity are crucial for managing diabetes and weight. Please remember that all medications carry potential side effects and should be used strictly according to a doctor's instructions, avoiding self-medication without proper guidance.